Enhancing plant-derived smart nano inhibitor in targeting mammalian target of rapamycin (mTOR) in breast cancer using Curcuma longa-derived compound curcumin.

Alamri, Ali H; Debnath, Sandip; Alqahtani, Taha; Alqahtani, Ali; Alshehri, Saad Ali; Ghosh, Arabinda

Enhancing plant-derived smart nano inhibitor in targeting mammalian target of rapamycin (mTOR) in breast cancer using Curcuma longa-derived compound curcumin.

Alamri, Ali H; Debnath, Sandip; Alqahtani, Taha; Alqahtani, Ali; Alshehri, Saad Ali; Ghosh, Arabinda.

Afiliação

Alamri AH; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.
Debnath S; Department of Genetics and Plant Breeding, Institute of Agriculture, Visva-Bharati University, Sriniketan, West Bengal, 731236, India.
Alqahtani T; Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.
Alqahtani A; Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.
Alshehri SA; Department of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Ghosh A; Microbiology Division, Department of Botany, Gauhati University, Guwahati, 781014, Assam, India. dra.ghosh@gauhati.ac.in.

Environ Sci Pollut Res Int ; 2023 Jan 31.

Article em En | MEDLINE | ID: mdl-36719580

Palavras-chave

Breast cancer; Curcumin; Lipid nanoparticles; Molecular docking; Molecular dynamics simulation; Nanocompounds; Signaling; Smart nanoparticle coating; mTOR (mammalian target of rapamycin)

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article