Identification of yeast <i>&#945;</i>-glucosidase inhibitors from <i>Pueraria lobata</i> by ligand fishing based on magnetic mesoporous silicon combined with knock-out/knock-in technology.

Xu, Jinfang; Fan, Zhiyu; Yang, Gangqiang; Yang, Yanan; Wu, Xinjie; Li, Tongtong; Wang, Qili; Gao, Jianping

Identification of yeast α-glucosidase inhibitors from Pueraria lobata by ligand fishing based on magnetic mesoporous silicon combined with knock-out/knock-in technology.

Xu, Jinfang; Fan, Zhiyu; Yang, Gangqiang; Yang, Yanan; Wu, Xinjie; Li, Tongtong; Wang, Qili; Gao, Jianping.

Afiliação

Xu J; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Fan Z; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Yang G; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Yang Y; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Wu X; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Li T; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Wang Q; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.
Gao J; School of Pharmaceutical Science, Shanxi Medical University, 56 Xinjian Road, Taiyuan 030001, People's Republic of China. jpgao123@163.com.

Food Funct ; 14(4): 1952-1961, 2023 Feb 21.

Article em En | MEDLINE | ID: mdl-36723126

Assuntos

Isoflavonas; Pueraria; alfa-Glucosidases/metabolismo; Inibidores de Glicosídeo Hidrolases/química; Isoflavonas/farmacologia; Ligantes; Fenômenos Magnéticos; Simulação de Acoplamento Molecular; Extratos Vegetais/farmacologia; Pueraria/química; Saccharomyces cerevisiae/metabolismo; Silício; Espectrometria de Massas em Tandem; Tecnologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pueraria / Isoflavonas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pueraria / Isoflavonas Idioma: En Ano de publicação: 2023 Tipo de documento: Article