[Two pairs of phloroglucinol enantiomers from Hypericum wightianum and their stereochemical structures].
Zhongguo Zhong Yao Za Zhi
; 48(2): 421-429, 2023 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-36725232
ABSTRACT
The chemical constituents in the ethanol extract of Hypericum wightianum(Hypericaceae) were purified by column chromatography and identified via magnetic resonance imaging(NMR), high-resolution mass spectrum, and circular dichroism. A total of 22 compounds were identified, including eight polyprenylated phloroglucinols(1-8), three chromones(9-11), and three terpenoids(14-16) and so on. Among them, compounds 16 and 17 were first reported in the genus Hypericum, and compounds 1-11, 14, 15, and 19 were first isolated from H. wightianum. Compounds 1-4 were previously reported as two pairs of enantiomers. This study reported the chiral resolutions and absolute configurations of compounds 1-4 for the first time.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
Hypericum
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article