Between therapy effect and false-positive result in animal experimentation.

Sosnowski, Pawel; Sass, Piotr; Stanislawska-Sachadyn, Anna; Krzeminski, Michal; Sachadyn, Pawel

Sosnowski, Pawel; Sass, Piotr; Stanislawska-Sachadyn, Anna; Krzeminski, Michal; Sachadyn, Pawel.

Afiliação

Sosnowski P; Laboratory for Regenerative Biotechnology, Gdansk University of Technology, ul. Narutowicza 11/12, 80-233 Gdansk, Poland.
Sass P; Laboratory for Regenerative Biotechnology, Gdansk University of Technology, ul. Narutowicza 11/12, 80-233 Gdansk, Poland.
Stanislawska-Sachadyn A; Department of Molecular Biotechnology and Microbiology, Gdansk University of Technology, ul. Narutowicza 11/12, 80-233 Gdansk, Poland.
Krzeminski M; Institute of Applied Mathematics, Faculty of Applied Physics and Mathematics, Gdansk University of Technology, ul. Narutowicza 11/12, 80-233 Gdansk, Poland.
Sachadyn P; Laboratory for Regenerative Biotechnology, Gdansk University of Technology, ul. Narutowicza 11/12, 80-233 Gdansk, Poland. Electronic address: psach@pg.edu.pl.

Biomed Pharmacother ; 160: 114317, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36736277

Assuntos

Experimentação Animal; Animais; Camundongos; Teorema de Bayes; Algoritmos; Aprendizado de Máquina; Resultado do Tratamento

Palavras-chave

Animal experimentation, pharmacoregeneration; False-positive results; Machine-learning; Naïve Bayes classifier; Sample size; Statistical significance; Support Vector Machine classifier

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Experimentação Animal Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Experimentação Animal Idioma: En Ano de publicação: 2023 Tipo de documento: Article