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Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions.
Braxton, Alicia M; Kiemen, Ashley L; Grahn, Mia P; Forjaz, André; Babu, Jaanvi Mahesh; Zheng, Lily; Jiang, Liping; Cheng, Haixia; Song, Qianqian; Reichel, Rebecca; Graham, Sarah; Damanakis, Alexander I; Fischer, Catherine G; Mou, Stephanie; Metz, Cameron; Granger, Julie; Liu, Xiao-Ding; Bachmann, Niklas; Almagro-Pérez, Cristina; Jiang, Ann Chenyu; Yoo, Jeonghyun; Kim, Bridgette; Du, Scott; Foster, Eli; Hsu, Jocelyn Y; Rivera, Paula Andreu; Chu, Linda C; Liu, Fengze; Niknafs, Noushin; Fishman, Elliot K; Yuille, Alan; Roberts, Nicholas J; Thompson, Elizabeth D; Scharpf, Robert B; Cornish, Toby C; Jiao, Yuchen; Karchin, Rachel; Hruban, Ralph H; Wu, Pei-Hsun; Wirtz, Denis; Wood, Laura D.
Afiliação
  • Braxton AM; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Kiemen AL; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Grahn MP; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Forjaz A; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Babu JM; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Zheng L; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Jiang L; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Cheng H; McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University, Baltimore, MD.
  • Song Q; Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD.
  • Reichel R; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China.
  • Graham S; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China.
  • Damanakis AI; State Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China.
  • Fischer CG; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Mou S; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Metz C; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Granger J; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Liu XD; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Bachmann N; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Almagro-Pérez C; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Jiang AC; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Yoo J; Department of Pathology, Molecular Pathology Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Kim B; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Du S; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Foster E; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Hsu JY; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Rivera PA; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Chu LC; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Liu F; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Niknafs N; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Fishman EK; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.
  • Yuille A; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Roberts NJ; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Thompson ED; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Scharpf RB; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Cornish TC; Department of Computer Science, Johns Hopkins University, Baltimore, MD.
  • Jiao Y; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Karchin R; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Hruban RH; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Wu PH; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Wirtz D; Department of Pathology, University of Colorado School of Medicine, Aurora, CO.
  • Wood LD; Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD.
bioRxiv ; 2023 Jan 28.
Article em En | MEDLINE | ID: mdl-36747709
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article