Hepatic artery disorders associated with alcoholism.
J Int Med Res
; 51(2): 3000605231153547, 2023 Feb.
Article
em En
| MEDLINE
| ID: mdl-36748484
ABSTRACT
OBJECTIVE:
We aimed to characterize the relationship between severe chronic alcoholism and hepatic arterial wall disorders in humans.METHODS:
We obtained hepatic arteries from 165 patients undergoing liver transplantation who were placed into two etiological groups an Alcoholism group and a Non-alcoholism group. We compared the age, sex, lipid profile, and histologic characteristics of the hepatic arteries (normal, reduction in luminal diameter of ≤10%, or atherosclerosis) of the participants in the two groups using multifactor analyses.RESULTS:
The Alcoholism group comprised 58 men and 40 women and the Non-alcoholism group comprised 63 men and 4 women. The mean ages of the groups were 52.5 ± 9.6 years and 44.2 ± 13.8 years, respectively. There were no circulating lipid abnormalities in any of the participants. In women, arterial disorders were found at a younger age than in men. Hepatic arterial disorders were more frequent in the non-alcoholic participants, and women with alcoholism showed less arterial narrowing.CONCLUSION:
The heavy consumption of alcoholic beverages is associated with a lower incidence of atherosclerosis of the hepatic artery in humans.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alcoolismo
/
Aterosclerose
/
Hepatopatias
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article