[Physiological reactions in the interface between cementless implants and bone]. / Physiologische Reaktionen im Interface zementfreier Implantate.

ABSTRACT

BACKGROUND: Surgical treatment of patients with osteoarthritis of the hip and persisting symptoms under conservative therapy has become increasingly important against the background of an aging population. OBJECTIVES: What are the physiological reactions in the interface between cementless implants and bone? METHODS: The literature is reviewed, expert opinions and animal models are analyzed and discussed. RESULTS: Surface coating of implants with hydroxyapatite or titanium can have positive effects on osteointegration. Additional local application of mediators might be beneficial for osteointegration in the future. CONCLUSION: Early peri-implant bone healing directly after implantation and late remodeling of the bone-implant interface are essential for secondary implant stability.