Real-world evidence for beneficial effects of dipyrone in 4,278 patients with pulmonary hypertension - Analysis of the risk of ventilation, hospitalization, and agranulocytosis.

Hertel, Moritz; Preissner, Saskia; Gohlke, Björn O; Kuebler, Wolfgang M; Hernandez, Gema; Akyüz, Mehmet; Preissner, Robert

Hertel, Moritz; Preissner, Saskia; Gohlke, Björn O; Kuebler, Wolfgang M; Hernandez, Gema; Akyüz, Mehmet; Preissner, Robert.

Afiliação

Hertel M; Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, Germany.
Preissner S; Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, Germany. Electronic address: saskia.preissner@charite.de.
Gohlke BO; Science-IT, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Philippstr. 12, 10115, Berlin, Germany.
Kuebler WM; Institute of Physiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Philippstr. 12, 10115, Berlin, Germany.
Hernandez G; Biomedical Informatics Group, Artificial Intelligence Department, E.T.S.I. Informáticos, Universidad Politécnica de Madrid, Spain.
Akyüz M; TriNetX, LLC, Cambridge, MA, USA.
Preissner R; Institute of Physiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Philippstr. 12, 10115, Berlin, Germany; Science-IT, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu

Eur J Pharmacol ; 943: 175567, 2023 Mar 15.

Article em En | MEDLINE | ID: mdl-36754194

Assuntos

Agranulocitose; Hipertensão Pulmonar; Humanos; Dipirona/efeitos adversos; Anti-Inflamatórios não Esteroides/uso terapêutico; Hipertensão Pulmonar/tratamento farmacológico; Hipertensão Pulmonar/induzido quimicamente; Hospitalização; Agranulocitose/tratamento farmacológico; Agranulocitose/induzido quimicamente; Agranulocitose/diagnóstico

Palavras-chave

Agranulocytosis; Dipyrone; Drug repositioning; Hospitalization; Metamizole; Pulmonary hypertension; Real-world data; Ventilation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agranulocitose / Hipertensão Pulmonar Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agranulocitose / Hipertensão Pulmonar Idioma: En Ano de publicação: 2023 Tipo de documento: Article