MicroRNAs in the Mouse Developing Retina.
Int J Mol Sci
; 24(3)2023 Feb 03.
Article
em En
| MEDLINE
| ID: mdl-36769311
ABSTRACT
The retina is among the highest organized tissues of the central nervous system. To achieve such organization, a finely tuned regulation of developmental processes is required to form the retinal layers that contain the specialized neurons and supporting glial cells to allow precise phototransduction. MicroRNAs are a class of small RNAs with undoubtful roles in fundamental biological processes, including neurodevelopment of the brain and the retina. This review provides a short overview of the most important findings regarding microRNAs in the regulation of retinal development, from the developmental-dependent rearrangement of the microRNA expression program to the key roles of particular microRNAs in the differentiation and maintenance of retinal cell subtypes.
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Base de dados:
MEDLINE
Assunto principal:
MicroRNAs
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article