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Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats.
Mairinger, Severin; Hernández-Lozano, Irene; Filip, Thomas; Löbsch, Mathilde; Stanek, Johann; Zeitlinger, Markus; Hacker, Marcus; Tournier, Nicolas; Wanek, Thomas; Ehrhardt, Carsten; Langer, Oliver.
Afiliação
  • Mairinger S; Department of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria; Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.
  • Hernández-Lozano I; Department of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
  • Filip T; Core Facility Laboratory Animal Breeding and Husbandry, Medical University of Vienna, 1090 Vienna, Austria; Center for Biomedical Research, Medical University of Vienna, 1090 Vienna, Austria.
  • Löbsch M; Core Facility Laboratory Animal Breeding and Husbandry, Medical University of Vienna, 1090 Vienna, Austria.
  • Stanek J; Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.
  • Zeitlinger M; Department of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
  • Hacker M; Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.
  • Tournier N; Laboratoire d'Imagerie Biomédicale Multimodale (BIOMAPS), Université Paris-Saclay, CEA, CNRS, Inserm, Service Hospitalier Frédéric Joliot, 91401 Orsay, France.
  • Wanek T; Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.
  • Ehrhardt C; School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
  • Langer O; Department of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria; Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090 Vienna, Austria. Electronic address: oliver.langer@meduniwien.ac.at.
Eur J Pharm Sci ; 183: 106404, 2023 Apr 01.
Article em En | MEDLINE | ID: mdl-36773747
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Membro 1 da Subfamília B de Cassetes de Ligação de ATP Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Membro 1 da Subfamília B de Cassetes de Ligação de ATP Idioma: En Ano de publicação: 2023 Tipo de documento: Article