Antibodies to repeat-containing antigens in <i>Plasmodium falciparum</i> are exposure-dependent and short-lived in children in natural malaria infections.

Raghavan, Madhura; Kalantar, Katrina L; Duarte, Elias; Teyssier, Noam; Takahashi, Saki; Kung, Andrew F; Rajan, Jayant V; Rek, John; Tetteh, Kevin K A; Drakeley, Chris; Ssewanyana, Isaac; Rodriguez-Barraquer, Isabel; Greenhouse, Bryan; DeRisi, Joseph L

Antibodies to repeat-containing antigens in Plasmodium falciparum are exposure-dependent and short-lived in children in natural malaria infections.

Raghavan, Madhura; Kalantar, Katrina L; Duarte, Elias; Teyssier, Noam; Takahashi, Saki; Kung, Andrew F; Rajan, Jayant V; Rek, John; Tetteh, Kevin K A; Drakeley, Chris; Ssewanyana, Isaac; Rodriguez-Barraquer, Isabel; Greenhouse, Bryan; DeRisi, Joseph L.

Afiliação

Raghavan M; University of California, San Francisco, San Francisco, United States.
Kalantar KL; Chan Zuckerberg Initiative, Redwood City, United States.
Duarte E; University of California, Berkeley, Berkeley, United States.
Teyssier N; University of California, San Francisco, San Francisco, United States.
Takahashi S; University of California, San Francisco, San Francisco, United States.
Kung AF; University of California, San Francisco, San Francisco, United States.
Rajan JV; University of California, San Francisco, San Francisco, United States.
Rek J; Infectious Diseases Research Collaboration, Kampala, Uganda.
Tetteh KKA; London School of Hygiene and Tropical Medicine, London, United Kingdom.
Drakeley C; London School of Hygiene and Tropical Medicine, London, United Kingdom.
Ssewanyana I; Infectious Diseases Research Collaboration, Kampala, Uganda.
Rodriguez-Barraquer I; London School of Hygiene and Tropical Medicine, London, United Kingdom.
Greenhouse B; University of California, San Francisco, San Francisco, United States.
DeRisi JL; Chan Zuckerberg Biohub, San Francisco, United States.

Elife ; 122023 02 15.

Article em En | MEDLINE | ID: mdl-36790168

Assuntos

Malária Falciparum; Malária; Adulto; Humanos; Criança; Plasmodium falciparum; Antígenos de Protozoários; Anticorpos Antiprotozoários; Epitopos; Proteínas de Protozoários

Palavras-chave

P. falciparum; antibodies; antigen profiling; human; immunology; infectious disease; inflammation; malaria; microbiology; natural immunity; phage display; repeat regions

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malária Falciparum / Malária Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malária Falciparum / Malária Idioma: En Ano de publicação: 2023 Tipo de documento: Article