Pirfenidone affects human cardiac fibroblast proliferation and cell cycle activity in 2D cultures and engineered connective tissues.

Meyer, Friederike Elisabeth Ugi; Santos, Gabriela Leao; Doan, Thao Phuong; DeGrave, Alisa Nicole; Bues, Bastian; Lutz, Susanne

Meyer, Friederike Elisabeth Ugi; Santos, Gabriela Leao; Doan, Thao Phuong; DeGrave, Alisa Nicole; Bues, Bastian; Lutz, Susanne.

Afiliação

Meyer FEU; Institute of Pharmacology and Toxicology, University Medical Center, Goettingen, Germany.
Santos GL; Institute of Pharmacology and Toxicology, University Medical Center, Goettingen, Germany.
Doan TP; Randall Centre for Cell and Molecular Biophysics, Kings College London, London, UK.
DeGrave AN; DZHK (German Centre for Cardiovascular Research) Partner Site, Goettingen, Germany.
Bues B; Institute of Pharmacology and Toxicology, University Medical Center, Goettingen, Germany.
Lutz S; Institute of Pharmacology and Toxicology, University Medical Center, Goettingen, Germany.

Naunyn Schmiedebergs Arch Pharmacol ; 396(8): 1687-1699, 2023 08.

Article em En | MEDLINE | ID: mdl-36800014

Assuntos

Tecido Conjuntivo; Fibroblastos; Humanos; Fibrose; Proliferação de Células; Ciclo Celular

Palavras-chave

Anti-fibrotic drugs; Cardiac fibrosis; Engineered connective tissues; Human cardiac fibroblasts; Pirfenidone

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Conjuntivo / Fibroblastos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Conjuntivo / Fibroblastos Idioma: En Ano de publicação: 2023 Tipo de documento: Article