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Spatial transcriptomics reveals niche-specific enrichment and vulnerabilities of radial glial stem-like cells in malignant gliomas.
Ren, Yanming; Huang, Zongyao; Zhou, Lingling; Xiao, Peng; Song, Junwei; He, Ping; Xie, Chuanxing; Zhou, Ran; Li, Menghan; Dong, Xiangqun; Mao, Qing; You, Chao; Xu, Jianguo; Liu, Yanhui; Lan, Zhigang; Zhang, Tiejun; Gan, Qi; Yang, Yuan; Chen, Tengyun; Huang, Bowen; Yang, Xiang; Xiao, Anqi; Ou, Yun; Su, Zhengzheng; Chen, Lu; Zhang, Yan; Ju, Yan; Zhang, Yuekang; Wang, Yuan.
Afiliação
  • Ren Y; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Huang Z; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Zhou L; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Xiao P; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Song J; Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second Hospital, Sichuan University, Chengdu, 610041, China.
  • He P; Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second Hospital, Sichuan University, Chengdu, 610041, China.
  • Xie C; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Zhou R; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Li M; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Dong X; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Mao Q; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • You C; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Xu J; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Liu Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Lan Z; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Zhang T; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Gan Q; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Yang Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Chen T; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Huang B; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Yang X; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Xiao A; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Ou Y; Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Su Z; Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Chen L; Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second Hospital, Sichuan University, Chengdu, 610041, China. luchen@scu.edu.cn.
  • Zhang Y; National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. yanzhang@scu.edu.cn.
  • Ju Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. juyanwestchina@126.com.
  • Zhang Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. 2012zykyx@sina.cn.
  • Wang Y; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China. wangyuan@scu.edu.cn.
Nat Commun ; 14(1): 1028, 2023 02 23.
Article em En | MEDLINE | ID: mdl-36823172
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Glioma Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Glioma Idioma: En Ano de publicação: 2023 Tipo de documento: Article