Lysine-Specific Demethylase 1 (LSD1)-Mediated Epigenetic Modification of Immunogenicity and Immunomodulatory Effects in Breast Cancers.

Lee, Dong Yeul; Salahuddin, Talha; Iqbal, Jabed

Lee, Dong Yeul; Salahuddin, Talha; Iqbal, Jabed.

Afiliação

Lee DY; Department of Anatomical Pathology, Singapore General Hospital, 20 College Road, Academia, Level 10, Diagnostics Tower, Singapore 169856, Singapore.
Salahuddin T; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.
Iqbal J; Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Grattan Street, Parkville, VIC 3010, Australia.

Curr Oncol ; 30(2): 2127-2143, 2023 02 09.

Article em En | MEDLINE | ID: mdl-36826125

Assuntos

Neoplasias da Mama; Humanos; Feminino; Neoplasias da Mama/patologia; Lisina/genética; Inibidores de Checkpoint Imunológico; Epigênese Genética; Histona Desmetilases/genética; Histona Desmetilases/metabolismo; Imunidade; Microambiente Tumoral

Palavras-chave

LSD1; breast cancer; epigenetics; immune-checkpoint; immunotherapy; lysine-specific demethylase 1; methylation; tumor immunogenicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Idioma: En Ano de publicação: 2023 Tipo de documento: Article