Acute PDE4 Inhibition Induces a Transient Increase in Blood Glucose in Mice.

Irelan, Daniel; Boyd, Abigail; Fiedler, Edward; Lochmaier, Peter; McDonough, Will; Aragon, Ileana V; Rachek, Lyudmila; Abou Saleh, Lina; Richter, Wito

Irelan, Daniel; Boyd, Abigail; Fiedler, Edward; Lochmaier, Peter; McDonough, Will; Aragon, Ileana V; Rachek, Lyudmila; Abou Saleh, Lina; Richter, Wito.

Afiliação

Irelan D; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Boyd A; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Fiedler E; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Lochmaier P; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
McDonough W; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Aragon IV; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Rachek L; Department of Pharmacology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Abou Saleh L; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.
Richter W; Department of Biochemistry & Molecular Biology and Center for Lung Biology, Whiddon College of Medicine, University of South Alabama, Mobile, AL 36688, USA.

Int J Mol Sci ; 24(4)2023 Feb 07.

Article em En | MEDLINE | ID: mdl-36834669

Assuntos

Insulinas; Inibidores da Fosfodiesterase 4; Camundongos; Animais; Nucleotídeo Cíclico Fosfodiesterase do Tipo 4/metabolismo; Inibidores da Fosfodiesterase 4/farmacologia; Glicemia; AMP Cíclico/metabolismo

Palavras-chave

2-deoxyglucose; PDE4; adrenergic signaling; blood glucose; cAMP-phosphodiesterase; insulin; skeletal muscle

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Fosfodiesterase 4 / Insulinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Fosfodiesterase 4 / Insulinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article