Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies.
Nutr Metab Cardiovasc Dis
; 33(4): 715-723, 2023 04.
Article
em En
| MEDLINE
| ID: mdl-36849317
ABSTRACT
BACKGROUND AND AIMS:
Conflicting evidence exists regarding the association between green tea consumption and the risk of coronary heart disease (CHD). We performed a meta-analysis to determine whether an association exists between them in cohort studies. METHODS ANDRESULTS:
We searched the PubMed and EMBASE databases for studies conducted until September 2022. Prospective cohort studies that provided relative risk (RR) estimates with 95% confidence intervals (CIs) for the association were included. Study-specific risk estimates were combined using a random-effects model. A total of seven studies, with 9211 CHD cases among 772,922 participants, were included. We observed a nonlinear association between green tea consumption and the risk of CHD (P for nonlinearity = 0.0009). Compared with nonconsumers, the RRs (95% CI) of CHD across levels of green tea consumption were 0.89 (0.83, 0.96) for 1 cup/day (1 cup = 300 ml), 0.84 (0.77, 0.93) for 2 cups/day, 0.85 (0.77, 0.92) for 3 cups/day, 0.88 (0.81, 0.96) for 4 cups/day, and 0.92 (0.82, 1.04) for 5 cups/day.CONCLUSIONS:
This updated meta-analysis of studies from East Asia suggests that green tea consumption may be associated with a reduced risk of CHD, especially among those with low-to-moderate consumption. Additional cohorts are still needed before we could draw a definitive conclusion. SYSTEMATIC REVIEW REGISTRATION PROSPERO CRD42022357687.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Chá
/
Doença das Coronárias
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article