Use of a Longer Aglycon Moiety Bearing Sialyl α(2â3) Lactoside on the Glycopolymer for Lectin Evaluation.
Polymers (Basel)
; 15(4)2023 Feb 17.
Article
em En
| MEDLINE
| ID: mdl-36850281
ABSTRACT
A polymerizable alcohol having 9 PEG repeats was prepared in order to mimic an oligosaccharide moiety. Sialyl α(2â3) lactose, which is known as a sugar moiety of GM3 ganglioside, was also prepared, and the polymerizable alcohol was condensed with the sialyl α(2â3) lactose derivative to afford the desired glycomonomer, which was further polymerized with or without acrylamide to give water-soluble glycopolymers. The glycopolymers had higher affinities than those of glycopolymers having sialyl lactose moieties with shorter aglycon moieties.
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MEDLINE
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En
Ano de publicação:
2023
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Article