Your browser doesn't support javascript.
loading
Evidence of a Set of Core-Function Genes in 16 Bacillus Podoviral Genomes with Considerable Genomic Diversity.
Ismail, Ahmed; Saini, Tanuj; Al Qaffas, Ahmed; Erill, Ivan; Caruso, Steven M; Temple, Louise; Johnson, Allison A.
Afiliação
  • Ismail A; Center for Biological Data Science, Virginia Commonwealth University, Richmond, VA 23284, USA.
  • Saini T; Center for Biological Data Science, Virginia Commonwealth University, Richmond, VA 23284, USA.
  • Al Qaffas A; Center for Biological Data Science, Virginia Commonwealth University, Richmond, VA 23284, USA.
  • Erill I; Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
  • Caruso SM; Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
  • Temple L; Integrated Science and Technology, James Madison University, Harrisonburg, VA 22807, USA.
  • Johnson AA; Center for Biological Data Science, Virginia Commonwealth University, Richmond, VA 23284, USA.
Viruses ; 15(2)2023 01 18.
Article em En | MEDLINE | ID: mdl-36851489
Bacteriophage genomes represent an enormous level of genetic diversity and provide considerable potential to acquire new insights about viral genome evolution. In this study, the genome sequences of sixteen Bacillus-infecting bacteriophages were explored through comparative genomics approaches to reveal shared and unique characteristics. These bacteriophages are in the Salasmaviridae family with small (18,548-27,206 bp) double-stranded DNA genomes encoding 25-46 predicted open reading frames. We observe extensive nucleotide and amino acid sequence divergence among a set of core-function genes that present clear synteny. We identify two examples of sequence directed recombination within essential genes, as well as explore the expansion of gene content in these genomes through the introduction of novel open reading frames. Together, these findings highlight the complex evolutionary relationships of phage genomes that include old, common origins as well as new components introduced through mosaicism.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bacillus / Fagos Bacilares Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bacillus / Fagos Bacilares Idioma: En Ano de publicação: 2023 Tipo de documento: Article