Organelle Communication: Joined in Sickness and in Health.
Physiology (Bethesda)
; 38(3): 0, 2023 05 01.
Article
em En
| MEDLINE
| ID: mdl-36856309
ABSTRACT
Organelles are membrane-lined structures that compartmentalize subcellular biochemical functions. Therefore, interorganelle communication is crucial for cellular responses that require the coordination of such functions. Multiple principles govern interorganelle interactions, which arise from the complex nature of organelles position, multilingualism, continuity, heterogeneity, proximity, and bidirectionality, among others. Given their importance, alterations in organelle communication have been linked to many diseases. Among the different types of contacts, endoplasmic reticulum mitochondria interactions are the best known; however, mounting evidence indicates that other organelles also have something to say in the pathophysiological conversation.
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Base de dados:
MEDLINE
Assunto principal:
Organelas
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article