Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars.

Skinner, Kasey R; Koga, Tomoyuki; Miki, Shunichiro; Gruener, Robert F; Grigore, Florina-Nicoleta; Torii, Emma H; Seelig, Davis M; Suzuki, Yuta; Kawauchi, Daisuke; Lin, Benjamin; Malicki, Denise M; Chen, Clark C; Benveniste, Etty N; Patel, Rakesh P; McFarland, Braden C; Huang, R Stephanie; Jones, Chris; Mackay, Alan; Miller, C Ryan; Furnari, Frank B

Skinner, Kasey R; Koga, Tomoyuki; Miki, Shunichiro; Gruener, Robert F; Grigore, Florina-Nicoleta; Torii, Emma H; Seelig, Davis M; Suzuki, Yuta; Kawauchi, Daisuke; Lin, Benjamin; Malicki, Denise M; Chen, Clark C; Benveniste, Etty N; Patel, Rakesh P; McFarland, Braden C; Huang, R Stephanie; Jones, Chris; Mackay, Alan; Miller, C Ryan; Furnari, Frank B.

Afiliação

Skinner KR; Division of Neuropathology, Department of Pathology, O'Neal Comprehensive Cancer Center and Comprehensive Neuroscience Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Koga T; Neuroscience Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Miki S; These authors contributed equally to this work.
Gruener RF; Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA.
Grigore FN; These authors contributed equally to this work.
Torii EH; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Seelig DM; These authors contributed equally to this work.
Suzuki Y; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Kawauchi D; Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA.
Lin B; Comparative Pathology Shared Resource, Masonic Cancer Center, University of Minnesota, St. Paul, MN 55108, USA.
Malicki DM; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Chen CC; Comparative Pathology Shared Resource, Masonic Cancer Center, University of Minnesota, St. Paul, MN 55108, USA.
Benveniste EN; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Patel RP; Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA.
McFarland BC; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Huang RS; Division of Neuropathology, Department of Pathology, O'Neal Comprehensive Cancer Center and Comprehensive Neuroscience Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jones C; Pathology, Rady Children's Hospital University of California San Diego, San Diego, CA 92123, USA.
Mackay A; Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA.
Miller CR; Department of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Furnari FB; Division of Molecular and Cellular Pathology, Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.