What can the plasma proteome tell us about platelets and (vice versa)?
Platelets
; 34(1): 2186707, 2023 Dec.
Article
em En
| MEDLINE
| ID: mdl-36894508
Platelets are key cellular elements of blood with plasma constituting the liquid component. Both platelets and proteins found in plasma rapidly work in unity to prevent/limit blood loss in response to blood vessel damage. Proteomics is the analysis of the entire protein complement of a cell, tissue, or organism under a specific, defined set of conditions. Of note, research to date has shown that platelet and plasma proteomes share many common proteins. In some disease scenarios, plasma proteomes can be used to identify platelet function or dysfunction, while in other scenarios, platelet-specific proteins are needed for physiological assessment. Thus, it may be beneficial to simultaneously study the plasma and platelet proteomes, thereby exploiting the considerable wealth of information provided under such circumstances.
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Base de dados:
MEDLINE
Assunto principal:
Plaquetas
/
Proteoma
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article