Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.

Santarpia, Mariacarmela; Ciappina, Giuliana; Spagnolo, Calogera Claudia; Squeri, Andrea; Passalacqua, Maria Ilenia; Aguilar, Andrés; Gonzalez-Cao, Maria; Giovannetti, Elisa; Silvestris, Nicola; Rosell, Rafael.

Afiliação

Santarpia M; Department of Human Pathology "G. Barresi", Medical Oncology Unit, University of Messina, Messina, Italy.
Ciappina G; Department of Human Pathology "G. Barresi", Medical Oncology Unit, University of Messina, Messina, Italy.
Spagnolo CC; Department of Human Pathology "G. Barresi", Medical Oncology Unit, University of Messina, Messina, Italy.
Squeri A; Department of Human Pathology "G. Barresi", Medical Oncology Unit, University of Messina, Messina, Italy.
Passalacqua MI; Department of Human Pathology "G. Barresi", Medical Oncology Unit, University of Messina, Messina, Italy.
Aguilar A; Oncology Institute Dr. Rosell, IOR, Dexeus University Hospital, Barcelona, Spain.
Gonzalez-Cao M; Oncology Institute Dr. Rosell, IOR, Dexeus University Hospital, Barcelona, Spain.
Giovannetti E; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
Silvestris N; Cancer Pharmacology Lab, Fondazione Pisana per La Scienza, San Giuliano, Italy.
Rosell R; Department of Human Pathology "G. Barresi", Medical Oncology Unit, University of Messina, Messina, Italy.