Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues.

Liu, Peng; Roberts, Sophie; Shoemaker, James T; Vukasinovic, Jelena; Tomlinson, Darren C; Speirs, Valerie

Liu, Peng; Roberts, Sophie; Shoemaker, James T; Vukasinovic, Jelena; Tomlinson, Darren C; Speirs, Valerie.

Afiliação

Liu P; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Roberts S; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom.
Shoemaker JT; Lena Biosciences, Atlanta, GA, United States of America.
Vukasinovic J; Lena Biosciences, Atlanta, GA, United States of America.
Tomlinson DC; School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
Speirs V; Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

PLoS One ; 18(3): e0283044, 2023.

Article em En | MEDLINE | ID: mdl-36928454

Assuntos

Neoplasias da Mama; Animais; Humanos; Feminino; Neoplasias da Mama/tratamento farmacológico; Técnicas de Cultura de Células/métodos; Mama; Células MCF-7; Tamoxifeno/farmacologia; Tamoxifeno/uso terapêutico; Linhagem Celular Tumoral

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Idioma: En Ano de publicação: 2023 Tipo de documento: Article