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Harnessing personalized tailored medicines to digital-based data-enriched edible pharmaceuticals.
Handa, Mayank; Afzal, Obaid; Beg, Sarwar; Nashik Sanap, Sachin; Kaundal, Ravinder K; Verma, Rahul K; Mishra, Awanish; Shukla, Rahul.
Afiliação
  • Handa M; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Raebareli, Lucknow, UP 226002, India. Electronic address: mayankhanda1991@gmail.com.
  • Afzal O; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi Arabia.
  • Beg S; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK. Electronic address: sarwar.beg@gmail.com.
  • Nashik Sanap S; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Raebareli, Lucknow, UP 226002, India.
  • Kaundal RK; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Raebareli (NIPER-R), Lucknow, UP 226002, India.
  • Verma RK; Institute of Nano Science and Technology (INST), SAS Nagar, Punjab 140306, India.
  • Mishra A; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, Changsari, Guwahati 781101, Assam, India.
  • Shukla R; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Raebareli, Lucknow, UP 226002, India. Electronic address: rahulshuklapharm@gmail.com.
Drug Discov Today ; 28(5): 103555, 2023 05.
Article em En | MEDLINE | ID: mdl-36931386
ABSTRACT
Tailoring drug products to personalized medicines poses challenges for conventional dosage forms. The prominent reason is the restricted availability of flexible dosage strengths in the market. Inappropriate dosage strengths lead to adverse drug reactions or compromised therapeutic effects. The situation worsens when the drug has a narrow therapeutic window. To overcome these challenges, data-enriched edible pharmaceuticals (DEEP) are novel concepts for designing solid oral products. DEEP have individualized doses and information embedded in quick response (QR) code form. When data are presented in a QR code, the information is printed with edible ink that contains the drug in tailored doses required for the patients.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Medicina de Precisão Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Medicina de Precisão Idioma: En Ano de publicação: 2023 Tipo de documento: Article