On frailty and accelerated aging during SARS-Cov-2: senescence.
Aging Clin Exp Res
; 35(4): 907-912, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-36935472
ABSTRACT
The COVID-19 pandemic is a burden for the worldwide healthcare systems. Whereas a clear age-dependent mortality can be observed, especially multimorbid and frail persons are at an increased risk. As bio-functional rather than calendrical age is in the meanwhile known to play a crucial role for COVID-19-related outcomes, aging-associated risk factors, overall prognosis and physiological age-related changes should be systematically considered for clinical decision-making. In this overview, we focus on cellular senescence as a major factor of biological aging, associated with organ dysfunction and increased inflammation (inflammaging).
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fragilidade
/
COVID-19
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article