Molecular mechanisms and targets of right ventricular fibrosis in pulmonary hypertension.

Bekedam, F T; Goumans, M J; Bogaard, H J; de Man, F S; Llucià-Valldeperas, A

Bekedam, F T; Goumans, M J; Bogaard, H J; de Man, F S; Llucià-Valldeperas, A.

Afiliação

Bekedam FT; Amsterdam UMC location Vrije Universiteit Amsterdam, PHEniX laboratory, Department of Pulmonary Medicine, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands.
Goumans MJ; Department of Cell and Chemical Biology, Leiden UMC, 2300 RC Leiden, the Netherlands.
Bogaard HJ; Amsterdam UMC location Vrije Universiteit Amsterdam, PHEniX laboratory, Department of Pulmonary Medicine, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands.
de Man FS; Amsterdam UMC location Vrije Universiteit Amsterdam, PHEniX laboratory, Department of Pulmonary Medicine, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands. Electronic address: fs.deman@amsterdamumc.nl.
Llucià-Valldeperas A; Amsterdam UMC location Vrije Universiteit Amsterdam, PHEniX laboratory, Department of Pulmonary Medicine, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands. Electronic address: a.lluciavalldeperas@amste

Pharmacol Ther ; 244: 108389, 2023 04.

Article em En | MEDLINE | ID: mdl-36940790

Assuntos

Insuficiência Cardíaca; Hipertensão Pulmonar; Humanos; Animais; Hipertensão Pulmonar/etiologia; Miocárdio/metabolismo; Fibrose; Ventrículos do Coração/metabolismo; Ventrículos do Coração/patologia; Fibroblastos/metabolismo; Remodelação Ventricular; Modelos Animais de Doenças

Palavras-chave

Fibrosis; Myocardial stiffness; Right ventricle; Therapy, cardiac fibroblast; Ventricular dysfunction

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insuficiência Cardíaca / Hipertensão Pulmonar Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insuficiência Cardíaca / Hipertensão Pulmonar Idioma: En Ano de publicação: 2023 Tipo de documento: Article