Spatial landscape of the tumor immune microenvironment.
Trends Cancer
; 9(6): 459-460, 2023 06.
Article
em En
| MEDLINE
| ID: mdl-36967255
ABSTRACT
Two recent studies published in Nature by Karimi et al. and Sorin et al. applied multiplexed imaging mass cytometry (IMC) to characterize the single-cell tumor immune landscapes covering millions of cells in brain tumors and lung adenocarcinomas (LUAD). They identified specific cell subtypes and cell-cell interactions that correlate with distinct clinical outcomes, thus providing valuable insights into tumor biology and prognostic prediction based on spatial architecture.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
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Adenocarcinoma de Pulmão
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Neoplasias Pulmonares
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article