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Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.
Sanders, Brian C; Pokhrel, Suman; Labbe, Audrey D; Mathews, Irimpan I; Cooper, Connor J; Davidson, Russell B; Phillips, Gwyndalyn; Weiss, Kevin L; Zhang, Qiu; O'Neill, Hugh; Kaur, Manat; Schmidt, Jurgen G; Reichard, Walter; Surendranathan, Surekha; Parvathareddy, Jyothi; Phillips, Lexi; Rainville, Christopher; Sterner, David E; Kumaran, Desigan; Andi, Babak; Babnigg, Gyorgy; Moriarty, Nigel W; Adams, Paul D; Joachimiak, Andrzej; Hurst, Brett L; Kumar, Suresh; Butt, Tauseef R; Jonsson, Colleen B; Ferrins, Lori; Wakatsuki, Soichi; Galanie, Stephanie; Head, Martha S; Parks, Jerry M.
Afiliação
  • Sanders BC; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA. sandersbc@ornl.gov.
  • Pokhrel S; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.
  • Labbe AD; Biological Sciences Division, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.
  • Mathews II; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • Cooper CJ; Stanford Synchrotron Radiation Lightsource, Menlo Park, CA, USA.
  • Davidson RB; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • Phillips G; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • Weiss KL; Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • Zhang Q; Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • O'Neill H; Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • Kaur M; Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
  • Schmidt JG; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
  • Reichard W; B-11 Bioenergy and Biome Sciences, Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, USA.
  • Surendranathan S; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, USA.
  • Parvathareddy J; Regional Biocontainment Laboratory, University of Tennessee Health Science Center, Memphis, TN, USA.
  • Phillips L; Regional Biocontainment Laboratory, University of Tennessee Health Science Center, Memphis, TN, USA.
  • Rainville C; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
  • Sterner DE; Progenra Inc., Malvern, PA, USA.
  • Kumaran D; Progenra Inc., Malvern, PA, USA.
  • Andi B; Biology Department, Brookhaven National Laboratory, Upton, NY, USA.
  • Babnigg G; Center for BioMolecular Structure, National Synchrotron Light Source II, Brookhaven National Laboratory, Upton, NY, USA.
  • Moriarty NW; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.
  • Adams PD; Biosciences Division, Argonne National Laboratory, Argonne, IL, USA.
  • Joachimiak A; Molecular Biosciences and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Hurst BL; Molecular Biosciences and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Kumar S; Department of Bioengineering, University of California, Berkeley, CA, USA.
  • Butt TR; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.
  • Jonsson CB; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA.
  • Ferrins L; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
  • Wakatsuki S; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
  • Galanie S; Progenra Inc., Malvern, PA, USA.
  • Head MS; Progenra Inc., Malvern, PA, USA.
  • Parks JM; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, USA.
Nat Commun ; 14(1): 1733, 2023 03 28.
Article em En | MEDLINE | ID: mdl-36977673
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatite C Crônica / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatite C Crônica / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article