[Analysis of anti-SARS-CoV-2 IgG antibody titers after mRNA booster vaccination in patients with nonmalignant hematological disorders].
Rinsho Ketsueki
; 64(2): 133-136, 2023.
Article
em Ja
| MEDLINE
| ID: mdl-36990734
ABSTRACT
In our facility, anti-SARS-CoV-2 mRNA vaccines were given to 21 patients, including 8 with aplastic anemia (AA), 3 with pure red cell aplasia (PRCA), and 10 with immune thrombocytopenic purpura (ITP), and IgG antibody titers were assessed one month after vaccinations. After receiving both a second vaccine and a booster shot, all patients with AA/PRCA treated with cyclosporine A aside from one, had IgG titers that were lower than the median levels of healthy controls. Even if prednisolone (PSL) doses did not go over 10 mg/day, ITP patients receiving PSL therapy were unable to achieve adequate levels of IgG after booster immunizations.
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Base de dados:
MEDLINE
Assunto principal:
Púrpura Trombocitopênica Idiopática
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Aplasia Pura de Série Vermelha
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COVID-19
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Doenças Hematológicas
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Anemia Aplástica
Idioma:
Ja
Ano de publicação:
2023
Tipo de documento:
Article