Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning.

Radford, Caelan E; Schommers, Philipp; Gieselmann, Lutz; Crawford, Katharine H D; Dadonaite, Bernadeta; Yu, Timothy C; Dingens, Adam S; Overbaugh, Julie; Klein, Florian; Bloom, Jesse D.

Afiliação

Radford CE; Molecular and Cellular Biology Graduate Program, University of Washington, and Basic Sciences Division, Fred Hutch Cancer Center, Seattle, Washington, 98109, USA.
Schommers P; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, Washington, 98109, USA.
Gieselmann L; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany.
Crawford KHD; German Center for Infection Research, partner site Bonn-Cologne, 50931 Cologne, Germany.
Dadonaite B; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany.
Yu TC; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany.
Dingens AS; German Center for Infection Research, partner site Bonn-Cologne, 50931 Cologne, Germany.
Overbaugh J; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany.
Klein F; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, Washington, 98109, USA.
Bloom JD; Department of Genome Sciences & Medical Scientist Training Program, University of Washington, Seattle, Washington, 98109, USA.

bioRxiv ; 2023 Mar 24.

Article em En | MEDLINE | ID: mdl-36993197

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article