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Age-dependent loss of hepatic SIRT1 enhances NLRP3 inflammasome signaling and impairs capacity for liver fibrosis resolution.
Adjei-Mosi, Jennifer; Sun, Qing; Smithson, Steven Blake; Shealy, Gavyn Lee; Amerineni, Krupa Dhruvitha; Liang, Zerong; Chen, Hanqing; Wang, Mei; Ping, Qinggong; Han, Jingyan; Morita, Masahiro; Kamat, Amrita; Musi, Nicolas; Zang, Mengwei.
Afiliação
  • Adjei-Mosi J; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Sun Q; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
  • Smithson SB; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Shealy GL; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
  • Amerineni KD; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Liang Z; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
  • Chen H; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Wang M; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
  • Ping Q; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Han J; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
  • Morita M; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Kamat A; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
  • Musi N; Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, San Antonio, Texas, USA.
  • Zang M; Department of Molecular Medicine, The University of Texas Health San Antonio, San Antonio, Texas, USA.
Aging Cell ; 22(5): e13811, 2023 05.
Article em En | MEDLINE | ID: mdl-36999514

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Ano de publicação: 2023 Tipo de documento: Article