13-Cis Retinoic Acid Induces Neuronal Differentiation in Daoy (Medulloblastoma) Cells Through Epigenetic Regulation of Topoisomerase IIß.

Chen, Jing; Zhang, Jing-Xia; Lei, Hai-Xia; Li, Xing-Yu; Yan, Yong-Xin; Wang, Yan-Ling; Lv, Yu-Hong; Yan, Yun-Li; Lei, Yu-Hua

Chen, Jing; Zhang, Jing-Xia; Lei, Hai-Xia; Li, Xing-Yu; Yan, Yong-Xin; Wang, Yan-Ling; Lv, Yu-Hong; Yan, Yun-Li; Lei, Yu-Hua.

Afiliação

Chen J; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China.
Zhang JX; Department of Radiology, Shijiazhuang Second Hospital, Shijiazhuang, Hebei, China.
Lei HX; Department of Oncology, Hebei General Hospital, Shijiazhuang, Hebei, China.
Li XY; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China.
Yan YX; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China.
Wang YL; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China.
Lv YH; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China.
Yan YL; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China.
Lei YH; Department of Cell Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China. lyh5615@163.com.

Appl Biochem Biotechnol ; 195(12): 7429-7445, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37000354

Assuntos

Neoplasias Cerebelares; Meduloblastoma; Criança; Humanos; Histonas/genética; Histonas/metabolismo; Isotretinoína/metabolismo; Meduloblastoma/genética; Meduloblastoma/patologia; Epigênese Genética; DNA Topoisomerases Tipo II/genética; DNA Topoisomerases Tipo II/metabolismo; Diferenciação Celular; Neoplasias Cerebelares/genética; Neoplasias Cerebelares/patologia; Tretinoína/farmacologia; Tretinoína/metabolismo

Palavras-chave

13-cis RA; Daoy cell; H3K27me3; JMJD3; Neuronal differentiation; Top IIß

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cerebelares / Meduloblastoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cerebelares / Meduloblastoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article