Gut microbiota regulates circadian oscillation in hepatic ischemia-reperfusion injury-induced cognitive impairment by interfering with hippocampal lipid metabolism in mice.

He, Zhigang; Liu, Yanbo; Li, Zhen; Sun, Tianning; Li, Zhixiao; Manyande, Anne; Xiang, Hongbing; Xiong, Jun

He, Zhigang; Liu, Yanbo; Li, Zhen; Sun, Tianning; Li, Zhixiao; Manyande, Anne; Xiang, Hongbing; Xiong, Jun.

Afiliação

He Z; Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu Y; Department of Emergency Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li Z; Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sun T; Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li Z; Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Manyande A; Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiang H; Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiong J; School of Human and Social Sciences, University of West London, London, UK.

Hepatol Int ; 17(6): 1645-1658, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37004699

Assuntos

Disfunção Cognitiva; Microbioma Gastrointestinal; Hepatopatias; Traumatismo por Reperfusão; Camundongos; Animais; RNA Ribossômico 16S; Metabolismo dos Lipídeos; Hepatopatias/genética; Traumatismo por Reperfusão/genética; Traumatismo por Reperfusão/metabolismo; Disfunção Cognitiva/etiologia; Hipocampo/metabolismo; Lipídeos

Palavras-chave

Circadian oscillation; Cognitive disorders; Dysbiosis; Fecal metabolites; Fecal microbiota transplantation; Gut microbiota; Hepatic ischemiareperfusion injury; Hippocampus; Lipid metabolism; Metabolomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Disfunção Cognitiva / Microbioma Gastrointestinal / Hepatopatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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