Polymer Dot-Gated Accumulation-Type Organic Photoelectrochemical Transistor for Urea Biosensing.
ACS Sens
; 8(4): 1835-1840, 2023 04 28.
Article
em En
| MEDLINE
| ID: mdl-37011305
ABSTRACT
Organic photoelectrochemical transistor (OPECT) biosensing represents a new platform interfacing optoelectronics and biological systems with essential amplification, which, nevertheless, are concentrated on depletion-type operation to date. Here, a polymer dot (Pdot)-gated accumulation-type OPECT biosensor is devised and applied for sensitive urea detection. In such a device, the as-designed Pdot/poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine] (PTAA) is validated as a superior gating module against the diethylenetriamine (DETA) de-doped poly(3,4-ethylenedioxythiophene)poly(styrene sulfonate) (PEDOTPSS) channel, and the urea-dependent status of Pdots has been shown to be sensitively correlated with the device's response. High-performance urea detection is thus realized with a wide linear range of 1 µM-50 mM and a low detection limit of 195 nM. Given the diversity of the Pdot family and its immense interactions with other species, this work represents a generic platform for developing advanced accumulation-type OPECT and beyond.
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Técnicas Biossensoriais
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article