Novel dual CAFs and tumour cell targeting pH and ROS dual sensitive micelles for targeting delivery of paclitaxel to liver cancer.

Guo, Chunjing; Zhang, Wei; Zhang, Qiaoyun; Su, Yanguo; Hou, Xiaoya; Chen, Qiang; Guo, Huimin; Kong, Ming; Chen, Daquan

Guo, Chunjing; Zhang, Wei; Zhang, Qiaoyun; Su, Yanguo; Hou, Xiaoya; Chen, Qiang; Guo, Huimin; Kong, Ming; Chen, Daquan.

Afiliação

Guo C; College of Marine Life Science, Ocean University of China, Qingdao, PR China.
Zhang W; Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, School of Pharmacy, Yantai University, Yantai, PR China.
Zhang Q; Department of Radiotherapy, Yantai Yuhuangding Hospital, The Affiliated Hospital of Qingdao University, Yantai, PR China.
Su Y; Department of Clinical Laboratory, Penglai Traditional Chinese Medicine Hospital, Yantai, PR China.
Hou X; Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, School of Pharmacy, Yantai University, Yantai, PR China.
Chen Q; Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, School of Pharmacy, Yantai University, Yantai, PR China.
Guo H; Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, School of Pharmacy, Yantai University, Yantai, PR China.
Kong M; Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, School of Pharmacy, Yantai University, Yantai, PR China.
Chen D; College of Marine Life Science, Ocean University of China, Qingdao, PR China.

Artif Cells Nanomed Biotechnol ; 51(1): 170-179, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37014123

Assuntos

Neoplasias Hepáticas; Paclitaxel; Humanos; Paclitaxel/química; Micelas; Espécies Reativas de Oxigênio; Neoplasias Hepáticas/tratamento farmacológico; Concentração de Íons de Hidrogênio; Sistemas de Liberação de Medicamentos; Ácido Hialurônico/química; Linhagem Celular Tumoral; Microambiente Tumoral

Palavras-chave

ROS response; Tumour-associated fibroblasts; anti-fibrosis; deep penetration; dual targeting; nanoparticles

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paclitaxel / Neoplasias Hepáticas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paclitaxel / Neoplasias Hepáticas Idioma: En Ano de publicação: 2023 Tipo de documento: Article