The prognostic value and biological functions of HFM1 in breast cancer.
Epigenomics
; 15(3): 147-166, 2023 02.
Article
em En
| MEDLINE
| ID: mdl-37020390
The role and function of the protein HFM1 in tumors remains unknown. We explored the functions and potential mechanism of HFM1 in breast cancer through several known databases, clinical samples and cell experiments. We found that HFM1 was downregulated in breast cancer with a poor prognosis. HFM1 may mediate ovarian steroidogenesis and participate in tamoxifen resistance of estrogen receptor-positive breast cancer cells. Here we first put forward the relationship between HFM1 and the prognosis of breast cancer, and provided relevant clues for mechanism exploration.
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MEDLINE
Assunto principal:
Neoplasias da Mama
/
Insuficiência Ovariana Primária
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article