Effect of reduced two-dose (1+1) schedule of 10 and 13-valent pneumococcal conjugate vaccines (Synflorix<sup>TM</sup> and Prevenar13<sup>TM)</sup>) on nasopharyngeal carriage and serotype-specific immune response in the first two years of life: Results from an open-labelled randomized controlled trial in Indian children.

Kawade, Anand; Dayma, Girish; Apte, Aditi; Telang, Nilima; Satpute, Meenakshi; Pearce, Emma; Roalfe, Lucy; Patil, Rakesh; Wang, Yanyun; Noori, Navideh; Gondhali, Arun; Juvekar, Sanjay; Oron, Assaf P; Sanghavi, Sonali; Goldblatt, David; Dagan, Ron; Bavdekar, Ashish

Effect of reduced two-dose (1+1) schedule of 10 and 13-valent pneumococcal conjugate vaccines (Synflorix^TM and Prevenar13^TM)) on nasopharyngeal carriage and serotype-specific immune response in the first two years of life: Results from an open-labelled randomized controlled trial in Indian children.

Kawade, Anand; Dayma, Girish; Apte, Aditi; Telang, Nilima; Satpute, Meenakshi; Pearce, Emma; Roalfe, Lucy; Patil, Rakesh; Wang, Yanyun; Noori, Navideh; Gondhali, Arun; Juvekar, Sanjay; Oron, Assaf P; Sanghavi, Sonali; Goldblatt, David; Dagan, Ron; Bavdekar, Ashish.

Afiliação

Kawade A; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India. Electronic address: anand.kawade@kemhrcvadu.org.
Dayma G; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Apte A; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Telang N; Department of Microbiology, KEM Hospital, Pune, India.
Satpute M; Department of Microbiology, KEM Hospital, Pune, India.
Pearce E; Infection, Immunity and Inflammation Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Roalfe L; Infection, Immunity and Inflammation Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Patil R; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Wang Y; Infection, Immunity and Inflammation Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Noori N; Institute for Disease Modeling, Global Health Division, Bill and Melinda Gates Foundation, 500 5th Ave N, Seattle, WA, USA.
Gondhali A; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Juvekar S; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Oron AP; Institute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Sanghavi S; Department of Microbiology, KEM Hospital, Pune, India.
Goldblatt D; Infection, Immunity and Inflammation Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Dagan R; The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Bavdekar A; Vadu Rural Health Program, KEM Hospital Research Centre, Pune, India. Electronic address: a.bavdekar@kemhrcpune.org.

Vaccine ; 41(19): 3066-3079, 2023 05 05.

Article em En | MEDLINE | ID: mdl-37045679

Assuntos

Infecções Pneumocócicas; Lactente; Humanos; Criança; Recém-Nascido; Pré-Escolar; Sorogrupo; Infecções Pneumocócicas/prevenção & controle; Anticorpos Antibacterianos; Vacinas Pneumocócicas; Vacinas Conjugadas; Imunidade

Palavras-chave

Pneumococcal carriage; Pneumococcal conjugate vaccines; Reduced dose regime; Serotype-specific antibodies

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas Idioma: En Ano de publicação: 2023 Tipo de documento: Article