Determination and disposition of meta-iodobenzylguanidine in plasma and heart of transporter-deficient mice by UPLC-MS/MS.

Talebi, Zahra; Jin, Yan; Baker, Sharyn D; Addison, Daniel; Sparreboom, Alex

Talebi, Zahra; Jin, Yan; Baker, Sharyn D; Addison, Daniel; Sparreboom, Alex.

Afiliação

Talebi Z; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
Jin Y; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
Baker SD; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
Addison D; Division of Cardiovascular Medicine, Department of Medicine, The Ohio State University, Columbus, OH, USA.
Sparreboom A; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, USA. Electronic address: sparreboom.1@osu.edu.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1222: 123699, 2023 May 01.

Article em En | MEDLINE | ID: mdl-37059009

Assuntos

3-Iodobenzilguanidina; Espectrometria de Massas em Tandem; Ratos; Camundongos; Animais; Espectrometria de Massas em Tandem/métodos; Cromatografia Líquida; Ratos Sprague-Dawley; Cromatografia Líquida de Alta Pressão/métodos; Reprodutibilidade dos Testes

Palavras-chave

Mouse plasma and heart; Pharmacokinetics; UPLC-MS/MS; mIBG

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: 3-Iodobenzilguanidina / Espectrometria de Massas em Tandem Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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