Intracellular persister: A stealth agent recalcitrant to antibiotics.

Personnic, Nicolas; Doublet, Patricia; Jarraud, Sophie

Personnic, Nicolas; Doublet, Patricia; Jarraud, Sophie.

Afiliação

Personnic N; CIRI, Centre International de Recherche en Infectiologie, CNRS UMR 5308, INSERM U1111, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Doublet P; Group Persistence and Single-Cell Dynamics of Respiratory Pathogens, Lyon, France.
Jarraud S; CIRI, Centre International de Recherche en Infectiologie, CNRS UMR 5308, INSERM U1111, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.

Front Cell Infect Microbiol ; 13: 1141868, 2023.

Article em En | MEDLINE | ID: mdl-37065203

ABSTRACT

ABSTRACT

The bulk of bacteria transiently evading appropriate antibiotic regimes and recovered from non-resolutive infections are commonly refer to as persisters. In this mini-review, we discuss how antibiotic persisters stem from the interplay between the pathogen and the cellular defenses mechanisms and its underlying heterogeneity.

Assuntos

Antibacterianos; Bactérias; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico

Palavras-chave

antibiotic; heterogeneity; infection; persisters; virulence

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bactérias / Antibacterianos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bactérias / Antibacterianos Idioma: En Ano de publicação: 2023 Tipo de documento: Article