A comparison between bilateral and unilateral thyroid eye disease.
Int Ophthalmol
; 43(8): 2957-2962, 2023 Aug.
Article
em En
| MEDLINE
| ID: mdl-37067696
ABSTRACT
PURPOSE:
To compare characteristics of unilateral vs. bilateral thyroid eye disease (TED).METHODS:
This retrospective analytical cross-sectional study was conducted on patients with TED who were evaluated at an academic referral center over a 6-year period. We compared demographics, activity (clinical activity score) and severity (EUGOGO classification) of TED, thyroid disease duration, TED duration, the time interval between thyroid and eye involvement, thyroid function status, and clinical signs between bilateral and unilateral TED.RESULTS:
Three hundred eighty-three patients including 213 females (55.6%), who had a mean age of 40.23 ± 13.72 years, were enrolled. Active TED was seen in 8.8% of bilateral and none of unilateral cases (P = 0.04). Bilateral TED patients had more severe disease (P = 0.001). The distribution of hyperthyroidism, hypothyroidism, and euthyroidism was significantly different between unilateral and bilateral groups (P = 0.001). Abnormal ocular motility was present in 26.3% versus 2.3% of bilateral and unilateral ones, respectively (P = 0.001). Proptosis was more prevalent in bilateral than unilateral cases (P = 0.001). We did not observe any statistically significant difference between the two groups in others variables.CONCLUSION:
Bilateral TED patients present with more severity, activity, movement abnormality, proptosis, and hyperthyroidism.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Oftalmopatia de Graves
/
Hipertireoidismo
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article