Paclitaxel induces pyroptosis by inhibiting the volume­sensitive chloride channel leucine­rich repeat­containing 8a in ovarian cancer cells.

Yang, Xiurou; Li, Chao; Liao, Xuzhen; Liu, Shiqing; Li, Xue; Hou, Xiuying; Wang, Kai; Yang, Haifeng; Gao, Lvfen; Zhu, Linyan

Paclitaxel induces pyroptosis by inhibiting the volumesensitive chloride channel leucinerich repeatcontaining 8a in ovarian cancer cells.

Yang, Xiurou; Li, Chao; Liao, Xuzhen; Liu, Shiqing; Li, Xue; Hou, Xiuying; Wang, Kai; Yang, Haifeng; Gao, Lvfen; Zhu, Linyan.

Afiliação

Yang X; Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Li C; Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Liao X; Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Liu S; Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Li X; Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong 510006, P.R. China.
Hou X; Department of Pathogen Biology, School of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Wang K; Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong 510006, P.R. China.
Yang H; Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong 510006, P.R. China.
Gao L; Department of Obstetrics and Gynecology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Zhu L; Department of Pharmacology, School of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.

Oncol Rep ; 49(6)2023 06.

Article em En | MEDLINE | ID: mdl-37083067

Assuntos

Neoplasias Ovarianas; Paclitaxel; Humanos; Feminino; Paclitaxel/farmacologia; Paclitaxel/uso terapêutico; Neoplasias Ovarianas/tratamento farmacológico; Neoplasias Ovarianas/metabolismo; Piroptose; Caspase 3/metabolismo; Leucina/farmacologia; Leucina/uso terapêutico; Canais de Cloreto; Linhagem Celular Tumoral; Cloretos/metabolismo; Cloretos/uso terapêutico

Palavras-chave

chloride channel; ovarian cancer; paclitaxel; pyroptosis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Paclitaxel Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Paclitaxel Idioma: En Ano de publicação: 2023 Tipo de documento: Article