Azole antifungals and inter-individual differences in drug metabolism: the role of pharmacogenomics and precision medicine.

Biswas, Mohitosh; Shobana, John; Jinda, Pimonpan; Sukasem, Chonlaphat

Biswas, Mohitosh; Shobana, John; Jinda, Pimonpan; Sukasem, Chonlaphat.

Afiliação

Biswas M; Department of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh.
Shobana J; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Jinda P; Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand.
Sukasem C; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Expert Opin Drug Metab Toxicol ; 19(3): 165-174, 2023 Mar.

Article em En | MEDLINE | ID: mdl-37089014

Assuntos

Antifúngicos; Farmacogenética; Humanos; Antifúngicos/efeitos adversos; Voriconazol/farmacologia; Citocromo P-450 CYP2C19/genética; Medicina de Precisão; Individualidade; Azóis/farmacologia; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo

Palavras-chave

Azole antifungals; dosing guidelines; genetic polymorphisms; precision medicine; safety and effectiveness

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacogenética / Antifúngicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacogenética / Antifúngicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article