The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts.

Choi, In Young; Ling, Jonathan; Zhang, Jian; Helmenstine, Eric; Walter, Wencke; Bergman, Riley; Philippe, Céline; Manley, James; Rouault-Pierre, Kevin; Li, Bing; Wiseman, Daniel; Ouseph, Madhu; Bernard, Elsa; Li, Xiao; Haferlach, Torsten; Fazal, Salman; Jain, Tania; Gocke, Christopher; DeZern, Amy; Dalton, W Brian.

Afiliação

Choi IY; Johns Hopkins University School of Medicine.
Ling J; Johns Hopkins University.
Zhang J; Columbia University.
Helmenstine E; Johns Hopkins University.
Walter W; MLL Münchner Leukämielabor GmbH.
Bergman R; Vanderbilt University.
Philippe C; Barts Cancer Institute, Queen Mary University of London.
Manley J; Columbia University.
Rouault-Pierre K; Barts Cancer Institute - Queen Mary University of London.
Li B; Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
Wiseman D; The University of Manchester.
Ouseph M; Weill Cornell Medical College.
Bernard E; Memorial Sloan Kettering Cancer Center.
Li X; Shanghai Jiao Tong University Affiliated Sixth People's Hospital.
Haferlach T; MLL Munich Leukemia Laboratory.
Fazal S; Allegheny Health Network.
Jain T; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University.
Gocke C; Johns Hopkins University School of Medicine.
DeZern A; Johns Hopkins University School of Medicine.
Dalton WB; Johns Hopkins Medicine.

Res Sq ; 2023 Apr 14.

Article em En | MEDLINE | ID: mdl-37090662

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article