Amino Acid Sulfinate Salts as Alkyl Radical Precursors.
Org Lett
; 25(17): 3157-3162, 2023 May 05.
Article
em En
| MEDLINE
| ID: mdl-37093619
ABSTRACT
A general approach to the synthesis of amino acid sulfinate salts from commercially available α-chiral hydroxylated amino acids is reported. These reagents are shown to be valuable precursors to alkyl radicals under mild photochemical oxidation conditions. The photochemically generated amino acid radicals engage readily with alkyl and aryl disulfide radical traps to afford a diverse suite of modified amino acids.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article