The Pheochromocytoma/Paraganglioma syndrome: an overview on mechanisms, diagnosis and management.
Int Braz J Urol
; 49(3): 307-319, 2023.
Article
em En
| MEDLINE
| ID: mdl-37115176
ABSTRACT
Pheochromocytomas/paragangliomas (PPGL) are rare, metastatic, and potentially fatal neuroendocrine tumors, often neglected because they present symptoms similar to other prevailing clinical conditions such panic syndrome, thyrotoxicosis, anxiety, hypoglycemia, etc., delaying diagnosis and treatment. The rate of diagnosis of PPGL has been increasing with the improvement in the measurement of catecholamine metabolites and the expanding availability of imaging procedures. Its essential genetic nature has been extensively investigated, comprising more than 20 genes currently related to PPGL and more new genes will probably be revealed. This overview will shed some light on the clinical, laboratory, topographical, genetic diagnosis, and management of PPGL.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paraganglioma
/
Feocromocitoma
/
Neoplasias das Glândulas Suprarrenais
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article