Cells resident to precision templated 40-µm pore scaffolds generate small extracellular vesicles that affect CD4<sup>+</sup> T cell phenotypes through regulatory TLR4 signaling.

Hady, T F; Hwang, B; Waworuntu, R L; Ratner, B D; Bryers, J D

Cells resident to precision templated 40-µm pore scaffolds generate small extracellular vesicles that affect CD4⁺ T cell phenotypes through regulatory TLR4 signaling.

Hady, T F; Hwang, B; Waworuntu, R L; Ratner, B D; Bryers, J D.

Afiliação

Hady TF; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA.
Hwang B; Center for Lung Biology, Department of Surgery, University of Washington Seattle, WA 98109, USA.
Waworuntu RL; Center for Lung Biology, Department of Surgery, University of Washington Seattle, WA 98109, USA.
Ratner BD; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA.
Bryers JD; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA. Electronic address: jbryers@uw.edu.

Acta Biomater ; 166: 119-132, 2023 08.

Article em En | MEDLINE | ID: mdl-37150279

Assuntos

Vesículas Extracelulares; Receptor 4 Toll-Like; Camundongos; Animais; Receptor 4 Toll-Like/metabolismo; Fator 88 de Diferenciação Mieloide/metabolismo; Proteômica; Transdução de Sinais; Linfócitos T CD4-Positivos; Vesículas Extracelulares/metabolismo; Fenótipo

Palavras-chave

Porous biomaterial; Pro-healing; T cell; TLR4; sEV signaling

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 4 Toll-Like / Vesículas Extracelulares Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 4 Toll-Like / Vesículas Extracelulares Idioma: En Ano de publicação: 2023 Tipo de documento: Article