Pnictogen Interactions with Nitrogen Acceptors.
Angew Chem Int Ed Engl
; 62(28): e202304960, 2023 Jul 10.
Article
em En
| MEDLINE
| ID: mdl-37155943
ABSTRACT
Stabilizing nitrogen pnictogen bond interactions were measured using molecular rotors. Intramolecular C=Oâ
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N interactions were formed in the bond rotation transition states which lowered the rotational barriers and increased the rates of rotation, as measured by EXSY NMR. The pnictogen interaction energies show a very strong correlation with the positive electrostatic potential on nitrogen, which was consistent with a strong electrostatic component. In contrast, the NBO perturbation and pyramidalization analyses show no correlation, suggesting that the orbital-orbital component is minor. The strongest C=Oâ
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N pnictogen interactions were comparable to C=Oâ
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C=O interactions and were stronger than C=Oâ
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Ph interactions, when measured using the same N-phenylimide rotor system. The ability of the nitrogen pnictogen interactions to stabilize transition states and enhance kinetic processes demonstrates their potential in catalysis and reaction design.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article