Systematic integration of protein-affecting mutations, gene fusions, and copy number alterations into a comprehensive somatic mutational profile.

Striker, Shawn S; Wilferd, Sierra F; Lewis, Erika M; O'Connor, Samantha A; Plaisier, Christopher L

Striker, Shawn S; Wilferd, Sierra F; Lewis, Erika M; O'Connor, Samantha A; Plaisier, Christopher L.

Afiliação

Striker SS; School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, AZ 85287-9709, USA.
Wilferd SF; School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, AZ 85287-9709, USA.
Lewis EM; School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, AZ 85287-9709, USA.
O'Connor SA; School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, AZ 85287-9709, USA.
Plaisier CL; School of Biological and Health Systems Engineering, Fulton Schools of Engineering, Arizona State University, Tempe, AZ 85287-9709, USA.

Cell Rep Methods ; 3(4): 100442, 2023 04 24.

Article em En | MEDLINE | ID: mdl-37159661

Assuntos

Variações do Número de Cópias de DNA; Fusão Gênica; Variações do Número de Cópias de DNA/genética; Mutação; Redes Reguladoras de Genes; Fenótipo

Palavras-chave

Systems Genetics Network Analysis; allelic heterogeneity; cancer; feedback loops; feedforward loops; gene regulatory networks; oncogene; somatic mutations; triad significance profiles; tumor suppressor gene

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fusão Gênica / Variações do Número de Cópias de DNA Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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