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An integrated network pharmacology approach reveals that Darutigenol reduces inflammation and cartilage degradation in a mouse collagen-induced arthritis model by inhibiting the JAK-STAT3 pathway.
Wang, Yong; Yan, Hui; Zhao, Long; He, Xue-Lai; Bao, Te-Ri-Gen; Sun, Xian-Duo; Yang, Yong-Cheng; Zhu, Shu-Yi; Gao, Xiao-Xu; Wang, An-Hua; Jia, Jing-Ming.
Afiliação
  • Wang Y; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Yan H; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Zhao L; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • He XL; School of Pharmaceutical Sciences, Hubei University of Medicine, Shiyan, 442000, People's Republic of China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Shiyan, 442000, People's Republic of China.
  • Bao TR; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Sun XD; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Yang YC; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Zhu SY; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Gao XX; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.
  • Wang AH; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. Electronic address: sywanganhua@163.com.
  • Jia JM; Teaching and Research Department of Chinese Materia Medica Resources, College of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. Electronic address: jiajingming@163.com.
J Ethnopharmacol ; 314: 116574, 2023 Oct 05.
Article em En | MEDLINE | ID: mdl-37160212
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Artrite Reumatoide / Cartilagem Articular Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Artrite Reumatoide / Cartilagem Articular Idioma: En Ano de publicação: 2023 Tipo de documento: Article