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Discovery of C-5 Pyrazole-Substituted Pyrrolopyridine Derivatives as Potent and Selective Inhibitors for Janus Kinase 1.
Lang, Jia-Jia; Lv, You; Kobe, Bostjan; Chen, Hongfei; Tan, Yan; Chen, Limei; Wang, Xuechuan; Mi, Pengbing; Zheng, Xing; Lin, Ying-Wu.
Afiliação
  • Lang JJ; Department of Pharmacy, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
  • Lv Y; Hengyang Medical College, School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China.
  • Kobe B; Key Lab of Protein Structure and Function of Universities in Hunan Province, University of South China, Hengyang 421001, China.
  • Chen H; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, Shaanxi 710021, China.
  • Tan Y; Xi'an Amazinggene Co., Ltd, Xi'an, Shaanxi 710026, China.
  • Chen L; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland 4072, Australia.
  • Wang X; Department of Pharmacy, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
  • Mi P; Department of Pharmacy, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
  • Zheng X; Department of Pharmacy, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
  • Lin YW; College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology, Xi'an, Shaanxi 710021, China.
J Med Chem ; 66(10): 6725-6742, 2023 05 25.
Article em En | MEDLINE | ID: mdl-37163463
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Inibidores de Janus Quinases Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Inibidores de Janus Quinases Idioma: En Ano de publicação: 2023 Tipo de documento: Article